Principal Scientist - Bioanalytical Assay Development

Location: Lebanon, NH

Department: Affinity Ligand Analytical Development

Type: Full Time

Min. Experience: Experienced

About Avitide

Avitide is a biotechnology company that provides high-performance affinity-based purification technologies and processes for the biopharmaceutical industry with an industry-leading timeframe.  Avitide’s disruptive approach to on-demand discovery and supply of exclusive affinity separation technologies is fundamentally changing the way biopharmaceutical development is being approached and how biopharmaceutical drug products are being defined.  To fulfill this mission, Avitide seeks a highly motivated and qualified candidate to facilitate the development and delivery of novel affinity separation technologies and processes for clinical and commercial biopharmaceutical drug products to Avitide’s growing roster of biopharmaceutical partners. The Avitide platform provides biopharmaceutical manufacturers with exclusive, high-yield, and high purity affinity separation technology that can controllably improve the drug product profile and accelerate the delivery of new biologics and vaccines to the clinic and market. 

Avitide's founding team brings substantial expertise and a track record of success in commercializing innovative biopharmaceutical discovery and manufacturing platform technologies.  Avitide is financed by top-tier venture capital firms such as Polaris Venture Partners, OrbiMed Advisors, SV Life Sciences, NeoMed Management, Mithril Capital Management, Sands Capital Ventures and Borealis Ventures.

Avitide is located in New Hampshire’s beautiful Upper Connecticut River Valley, and is minutes from Dartmouth College, the Geisel School of Medicine, the Thayer School of Engineering, the Tuck School of Business, and Dartmouth-Hitchcock Medical Center.  The surrounding New Hampshire and Vermont areas are renowned for its premier skiing, hiking, kayaking, and biking.  Avitide offers individually tailored compensation packages comprised of competitive salary, bonus, benefits, and equity components.

 

About This Position

The candidate will provide foundational expertise and technical leadership to direct the analytical support of biopharmaceutical purification programs and product development.  Avitide seeks candidates who are highly self-motivated and can work in a collaborative fashion with other interdisciplinary team members. The ideal candidate will partner with project teams to ensure preparedness for each new discovery campaigns. A key facet is the training and mentoring colleagues in analytical technology and methods.

Qualifications and Experience

Degree (MS/PhD) in sciences or engineering

  • 5+ years of experience in a laboratory setting
  • Detailed experience in bioanalytical method development for finished biopharmaceuticals, biomarkers or DMPK. Appropriate techniques include
    • ELISA and other immunoassay platforms
    • Multiplexed assays
    • UPLC, HPLC and MS
    • Capillary electrophoresis and charge variant analysis
    • Enzymatic activity and biochemical assays
  • Expertise in development of quantitative assays across many different analytical techniques and analytical validation
  • Biopharmaceutical product analysis (release assays) including product purity, titer, activity and impurity analysis (e.g. HCP, DNA)
  • Understanding of statistical methods to ensure quality of results in a research environment
  • Demonstrated history of strong hands-on ability, problem solving, and independent experimental design and execution

Duties and Responsibilities

  • Design and development of analytical assays to monitor critical quality attributes for our partner’s drug candidates
  • Liaise with external collaborators and guide the technical transfer of analytical methods
  • Train and mentor less experienced colleagues in the use of analytical assays
  • Performance of quantitative analytical assays in a timely manner
  • Implement and oversee appropriate quality assurance mechanisms
  • Ability to innovate and introduce new techniques to improve the power of Avitide’s ligand generation platform

Avitide Cultural Qualities

  • Demonstrate creativity and innovation
  • Actively contribute to our collaborative team culture
  • Willingness to adhere to written procedures and instructions
  • Agile and quick to adapt
  • Eager to learn and develop professional skills
  • Excellent and timely communication skills
Apply for this Position
* Required fields
First name*
Last name*
Email address*
Location *
Phone number*
Resume*

Attach resume as .pdf, .doc, .docx, .odt, .txt, or .rtf (limit 5MB) or paste resume

Paste your resume here or attach resume file

Cover Letter
What’s your citizenship / employment eligibility?*
What’s your highest level of education completed?*
College or University*
LinkedInLinkedIn profile URL:
Earliest start date?*
In 150 characters or fewer, tell us what makes you unique. Try to be creative and say something that will catch our eye!*
References: Please enter names and contact information: